Association of proton pump inhibitor use with altered calcium metabolism and bone fractures
Effects of different courses of proton pump inhibitor on upper gastrointestinal tract rehaemorrhagia in non-steroidal anti-inflammatory drugs induced ulcer
Esomeprazole is a new member of proton pump inhibitors (PPI) with strong suppressive effects on gastric acid secretion.
Objective to clarify whether proton pump inhibitors (PPIs) stimulate Cyclooxygenase-2 (COX-2) expression in rat gastric mucosa.
Patients with demonstrated reflux by pH study or with reflux symptoms after surgery should be treated long-term with proton pump inhibitors.
But the drugs raise the risk of stomach bleeding, so they also prescribe Nexium, made by AstraZeneca, or a rival drug in a group known as proton pump inhibitors.
