Janus Kinase Inhibitor AG490 Blocks Stat3 Signaling Pathway and Reverses Immunosuppression in Hepatic Cancer Cells;
The Effects of AG490 on the Metabolic of Human Fat Cells in Leptin of Higher Physiological Concentration
结论AG490作为一种酪氨*激酶抑制剂,能影响正常细胞的功能。
目的研究特异*炎症介质阻断剂AG490提高极限肝切除术后大鼠生存率的机制。
结果AG490能显著延长移植物存活时间,与环孢素a联用有协同效应,作用更强。